Optics-free Imaging
for Drug Discovery

Real-time, high resolution, live-cell assays
using our electronic platform

+24 Hours
+48 Hours
+72 Hours

Spinning out from Harvard University, CytoTronics is building the next generation of complementary metal-oxide-semiconductor (CMOS) electronics technology for cell measurement and manipulation to produce unique electrical and electrochemical readouts that are not available in today’s cell-based drug screening market.

1

Multi-parametric

Combining cell kinetics, barrier function, metabolic state, and electrophysiology measurements and manipulations from the same cell culture

2

Live-cell

Delivering non-invasive and label free measurements through the whole duration of the assay – quality data extracted from living cells as they culture

3

High-resolution

Generating optics-free images to understand what is happening down to a single cell – overcome traditional whole-well aggregate readouts

High-resolution, Single-cell,
and In situ Operations

Our real-time, bioinformatics platform spans cell measurement and manipulation to further drug discovery and improve treatments in critical areas of healthcare from cancer, to cardiac to gastrointestinal disease.

We are re-engineering life science data acquisition by combining traditional low-resolution, electrochemical cell-assay techniques with a 21st century thrust of semiconductor technology.

CMOS-powered
Measurement
and Manipulation

By designing and developing cell culture plates with embedded high-density electronic systems, our technology will accelerate the drug discovery pipeline in broad therapeutic areas towards the IND stage (Investigational New Drug Application).

Kinetics

Investigate mechanism of actions, cellular growth and death, or movement

Cell Manipulation

Create customized wound healing assays or form repeatable co-cultures

Barrier Function

Perform spatial TEER measurements to accurately assess cell-cell junction integrity

Redox Metabolism

Visualize metabolic state of cells, investigate oxidative stress, antioxidant capacity, or mechanism of cell-death

Electrophysiology

Measure & stimulate the electrical signals of excitable cells such as cardiomyocytes or neurons

News & Publications

Nature Nanotechnology

CMOS nanoelectrode array for all-electrical intracellular electrophysiological imaging.​

News & Publications

Nature Nanotechnology

CMOS nanoelectrode array for all-electrical intracellular electrophysiological imaging.​

News & Publications

Nature Biomedical Engineering ​

A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons​

News & Publications

Nature Biomedical Engineering ​

A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons​

News & Publications

IEEE Journal of Solid-State Circuits 2020

The design of a CMOS nanoelectrode array with 4096 current-clamp/voltage-clamp amplifiers for intracellular recording/stimulation of mammalian neurons​

News & Publications

IEEE Journal of Solid-State Circuits 2020

The design of a CMOS nanoelectrode array with 4096 current-clamp/voltage-clamp amplifiers for intracellular recording/stimulation of mammalian neurons​

News & Publications

Lab on a Chip (2022)

New electrochemical techniques using a CMOS-MEA measures cell attachment, growth/wound healing, cell-cell adhesion, metabolic state, and redox properties for cell-biology.

News & Publications

Lab on a Chip (2022)

New electrochemical techniques using a CMOS-MEA measures cell attachment, growth/wound healing, cell-cell adhesion, metabolic state, and redox properties for cell-biology.

Our Team​

We are a team of scientists and engineers
revolutionizing drug discovery by re-engineering life
science data acquisition.

Our

Team

Careers

Resume Drop for Future Opportunities

Don’t see your perfect role, but interested in developing a breakthrough technology targeting immediate drug discovery applications? We don’t want to let a job description stop you from applying and are always looking for high performers to join our team.

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Careers

RESUME DROP FOR FUTURE OPPORTUNITIES

Don’t see your perfect role, but interested in developing a breakthrough technology targeting immediate drug discovery applications? We don’t want to let a job description stop you from applying and are always looking for high performers to join our team.

JOIN OUR MAILING LIST

At the heart of Boston's south end at AgilityLabs, CytoTronics is proximate to highways 93 & 90, the Broadway red-line T-stop, downtown Boston, & the Seaport district.

Contact us

Email: contact@cytotronics.com

Headquarters: 38 Wareham St, Boston, MA 02118