Endothelial barrier integrity is vital for vascular function and homeostasis, and its dysfunction can lead to conditions like inflammation and cardiovascular disease. Tracking subtle, transient changes in tissue barrier in vitro is essential to understanding barrier function and developing therapeutics for vascular disorders.
In this application note, you will explore:
- How CytoTronics’ electrical imaging platform can accurately and sensitively measure barrier with the high spatial density of its electrodes
- The advantage of using non-destructive measurements to capture real-time changes in cell culture and barrier dynamics
- Multi-modal, longitudinal data demonstrating barrier response to Adenosine, a potential therapeutic target for vascular dysfunction
Measuring real-time development of tissue barrier in HCAEC cells.
