Tissue barriers play a vital role in maintaining homeostasis and protecting the body from pathogens and toxins. Accurately measuring these barriers in vitro is critical for modeling disease and evaluating therapeutic effects, yet traditional approaches like TEER assays often lack precision and temporal resolution.
In this technical note, you will explore:
- The limitations of TEER assays in assessing barrier changes
- How CytoTronics’ impedance-based platform measures real-time changes in barrier structure and function
- Pharmacological data demonstrating both weakening and strengthening of tissue barrier in intestinal epithelial cell models
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Measuring tissue barrier with electrical imaging in 4 different cell lines.
